Trexamain (Tranexamic Acid 250 mg & 500 mg Capsules) is an oral antifibrinolytic medication used to prevent and reduce excessive bleeding in various medical conditions. Tranexamic acid works by inhibiting fibrinolysis, the process that breaks down blood clots, thus helping to stabilize clots and prevent unwanted bleeding. Trexamain is commonly prescribed for conditions like heavy menstrual bleeding (menorrhagia), postoperative bleeding, dental procedures in patients with bleeding disorders, and trauma-related bleeding. It is also used in individuals with certain bleeding disorders, such as hemophilia, to prevent excessive bleeding during surgeries or dental procedures.
Key Features and Benefits:
- Antifibrinolytic Action: Tranexamic acid prevents the breakdown of blood clots by inhibiting the enzyme plasmin, which plays a crucial role in fibrinolysis. This helps reduce and prevent excessive bleeding.
- Heavy Menstrual Bleeding (Menorrhagia): Trexamain is effective in reducing heavy menstrual bleeding, making it an important treatment option for women experiencing menorrhagia.
- Postoperative and Trauma Bleeding: The medication is frequently used after surgeries, dental extractions, or trauma to control excessive bleeding.
- Prevention of Bleeding in Hemophilia: Trexamain can be used in patients with hemophilia to prevent bleeding during surgical or dental procedures.
- Oral Administration: Available in 250 mg and 500 mg capsules for flexible dosing options depending on the severity of bleeding or the specific condition being treated.
- Improves Quality of Life: By controlling excessive bleeding, Trexamain helps patients maintain their normal daily activities with less concern about significant blood loss.
Usage Instructions:
- Dosage:
- Heavy Menstrual Bleeding (Menorrhagia):
- Adults: Typically, 1000 mg (two 500 mg capsules) taken three times daily for up to 5 days during menstruation.
- Postoperative Bleeding:
- Adults: Dosages may vary depending on the procedure and risk of bleeding. A typical regimen involves 1000 mg (two 500 mg capsules) taken three times daily for several days.
- Bleeding Disorders (e.g., Hemophilia):
- Adults: 1000 mg (two 500 mg capsules) taken two to three times daily during or following surgery, as directed by your healthcare provider.
- Heavy Menstrual Bleeding (Menorrhagia):
- Administration:
- Take Trexamain capsules orally with water.
- Capsules can be taken with or without food, although taking with food may help minimize potential stomach discomfort.
- Frequency:
- Typically taken two to three times daily, depending on the condition and severity of bleeding.
- Follow the dosing schedule prescribed by your healthcare provider.
- Duration of Treatment:
- For heavy menstrual bleeding, Trexamain is usually taken for up to 5 days during menstruation.
- For other conditions, the duration of treatment will depend on the specific medical situation and your healthcare provider’s recommendations.
- Missed Dose:
- If you miss a dose, take it as soon as you remember.
- If it is near the time of your next dose, skip the missed dose and resume your regular schedule.
- Do not take two doses at the same time to make up for a missed dose.
Precautions:
- Consult a Healthcare Provider: Always use Trexamain under the supervision of a qualified healthcare professional to ensure appropriate treatment and to minimize risks.
- Medical Conditions: Inform your healthcare provider if you have a history of blood clots, deep vein thrombosis (DVT), pulmonary embolism (PE), or any other thromboembolic disorders, as tranexamic acid may increase the risk of clotting in these conditions.
- Kidney Function: Tranexamic acid is excreted primarily through the kidneys. Patients with kidney disease or impaired kidney function may require dosage adjustments.
- Pregnancy and Breastfeeding: Consult your healthcare provider before using Trexamain if you are pregnant, planning to become pregnant, or breastfeeding. While tranexamic acid is generally considered safe during pregnancy, it should only be used when clearly needed.
- Drug Interactions: Inform your healthcare provider about all other medications you are taking, especially other anticoagulants (blood thinners) or hormonal medications, as these may interact with tranexamic acid.
Possible Side Effects:
- Common Side Effects:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Headache
- Less Common Side Effects:
- Dizziness or lightheadedness
- Fatigue
- Muscle cramps or pain
- Serious Side Effects (Seek Medical Attention Immediately):
- Signs of a blood clot, such as pain, swelling, warmth, or redness in the legs (deep vein thrombosis), chest pain, or difficulty breathing (pulmonary embolism)
- Vision changes or eye pain, which could indicate serious eye problems like retinal vein occlusion
- Signs of allergic reactions, including rash, itching, swelling, or difficulty breathing
Storage Instructions:
- Temperature: Store Trexamain capsules at room temperature, between 15°C to 30°C (59°F to 86°F), away from direct sunlight and moisture.
- Accessibility: Keep the medication out of reach of children to prevent accidental ingestion.
- Packaging Integrity: Ensure that the blister packs or bottles are tightly sealed after each use to protect the capsules from environmental factors and maintain their efficacy.
- Expiration: Do not use the capsules beyond the expiration date indicated on the packaging. Discard any unused medication after this date.